Identification of a Herpes Simplex Labialis Susceptibility Region on Human Chromosome 21
نویسندگان
چکیده
منابع مشابه
Recurrent herpes simplex labialis: selected therapeutic options.
Recurrent infection with herpes simplex virus 1 (HSV1), called herpes simplex labialis (HSL), is a global problem for patients with normal immune systems. An effective management program is needed for those with frequent HSL recurrences, particularly if associated morbidity and life-threatening factors are present and the patient's immune status is altered. Over the past 20 years, a variety of ...
متن کاملTreatment of recurrent herpes simplex labialis with levamisole.
Because deficient immune responses may play a contributory role in recurrent herpes simplex labialis, an immunomodulating agent, levamisole, has been advocated for therapy. Forty-two patients with a high frequency of recurrent herpes simplex labialis were followed for a mean of 7.8 months (range 4 to 12) and treated for 3 days at the onset of each episode of herpes with one of three different d...
متن کاملSusceptibility to herpes simplex labialis conferred by the gene encoding apolipoprotein E.
To the Editor—In a recent issue of the Journal, Hobbs et al. [1] describe their identification of a region on the long arm of human chromosome 21 that is associated with susceptibility to herpes simplex labialis (HSL). This location is of special interest to those who, like us, work on Alzheimer disease, because it includes the gene encoding the amyloid precursor protein and several other genes...
متن کاملA Preliminary Study on the Molecular Identification of Herpes Simplex Virus Type 1 in Iranian Population
Herpes Simplex Virus Type 1 (HSV-1) is a member of the Herpesviridae family that causes herpetic disease in human. During the last 25-30 years, many investigations have been conducted on pathogenesis and molecular biology of this virus in several countries. In Iran HSV-1 has been isolated from patients and detected using immunological techniques. In this study, we investigated the molecular asp...
متن کاملSurveillance for antiviral-agent-resistant herpes simplex virus in the general population with recurrent herpes labialis.
In a general population survey in the United States, the prevalence of antiviral-agent-resistant herpes simplex virus was very low among more than 1,000 isolates from individuals with an episode of recurrent herpes labialis not treated with topical antiviral agents. Two isolates had borderline resistance to acyclovir (0.2%), and all were susceptible to penciclovir.
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2008
ISSN: 0022-1899,1537-6613
DOI: 10.1086/525540